Reuse the enzyme
Retain the catalyst for repeated batches or extended flow campaigns.
INDUSTRIAL ENZYME IMMOBILISATION
Immobilised enzymes.
Move the process.
Multi-tonne quantities. From £349/kg.
Choose a product or develop a tailored solution.
ENGINEERED AT THE SURFACE.
DESIGNED AROUND YOUR PROCESS.Conceptual visualisation · not to scale
Up to 8 functional groupsCatalyst retention & reuseBeads · Cartridges · ModulesIndustrial technical support
WHY IMMOBILISE?
Why immobilise
your enzymes?
Keep catalytic activity in the process.
Build the commercial case around productive lifetime.
Lower enzyme cost
Spread catalyst investment over more product when useful activity is retained.
Simplify separation
Separate the solid biocatalyst from the process stream and reduce downstream enzyme removal.
Enable continuous flow
Hold the catalyst in place while substrate moves through a controlled reactor.
The benefit is measured in your process: conversion, catalyst lifetime, leaching and cost per unit of product.
Find your biocatalyst.
Select an existing enzyme, then choose beads, a cartridge or a module.
Browse products ↗02 / DEVELOP WITH USBuild your solution.
Your enzyme, reaction or novel use case. We develop the immobilisation route with you.
Explore bespoke development ↗01 / THE SURFACE MAKES THE DIFFERENCE
Functionalised silica.
Built for your enzyme.
We offer silica materials with up to eight different functional groups, giving your immobilisation project a broader starting point.
Bring us an enzyme, a target reaction or a new use case. Together, we can explore the support chemistry and process format that fit.
Discuss support functionalisation ↗ENGINEERED SILICA SUPPORTSurface functionality is specified for each project.
Schematic only; group identities and distribution are not represented.
Schematic only; group identities and distribution are not represented.
02 / ONE PLATFORM. THREE LEVELS OF INTEGRATION.
Immobilised enzymes.
Three process formats.
From catalyst in your reactor
to a dedicated processing system.
01 / CATALYST
Biocatalyst beads
Immobilised enzyme on engineered silica. Load the catalyst into your own batch or flow reactor.
- Flexible reactor integration
- Retain or separate for reuse
- Multi-tonne catalyst supply
02 / FLOW REACTOR
Flow cartridges
A contained catalyst bed in a ready-to-connect format. Put biocatalysis directly into your fluid line.
- Contained enzyme bed
- Straightforward replacement
- Screening and process development
03 / INTEGRATED SYSTEM
Dedicated modules
Biocatalysts and process equipment brought together for a defined industrial duty.
- Controlled processing
- Flow and residence-time management
- Project-specific integration
Format illustrations are schematic. Final catalyst, connections and system configuration are agreed for your application.
INDUSTRIAL MODULE DESIGN ENVELOPE
Think beyond
the laboratory.
5,000L/h
Up to this module throughput
20–95°C
Module heating range
>95%
Heat-recovery design target
03 / ESTABLISHED PROCESSES. UNEXPLORED POSSIBILITIES.
Your next process
could start here.
Tell us what the catalyst needs to achieve.
We’ll work backwards from the process.
SELECTIVITY / REUSE / CONTINUOUS OPERATION
Make the catalyst
part of the process.
Explore immobilised biocatalysts for selective transformations, ester synthesis and process intensification. Start with your substrate, solvent system and product specification.
DEFINE SUCCESS
Explore an industrial project ↗Conversion · Selectivity · Catalyst lifetime · Product purity
CHOOSE AN EXISTING BIOCATALYST
Explore our
immobilised enzymes.
Multi-tonne supply. Prices from £349/kg.
Select your enzyme and preferred format.
YOUR SELECTED BIOCATALYST
Enquire about this product ↗Immobilised CALA lipase
Need an enzyme that isn’t listed? We can develop a solution for your application ↗
BESPOKE IMMOBILISATION DEVELOPMENT
Custom enzyme
immobilisation.
Our custom enzyme immobilization service develops a tailored solution around your enzyme or target reaction: support chemistry, immobilisation conditions, catalyst performance and the final reactor format.
Start with the duty.
Reaction, feed composition, solvent, operating window and required throughput.
Find the right surface.
Compare support functionality, immobilisation conditions and retained catalytic activity.
Measure useful lifetime.
Track leaching, conversion, pressure drop and performance through repeated operation.
Choose the final format.
Translate the results into bead supply, a cartridge or a dedicated module.
FIND YOUR STARTING POINT
What do you
want to build?
Choose the closest description for an initial format suggestion.
YOUR STARTING POINT
Biocatalyst beads
Discuss an immobilised preparation for screening in your existing reactor.
Discuss this route ↗USEFUL TO KNOW
Built around
your requirements.
Can you work with our enzyme?
Yes. We welcome enquiries for custom immobilisation, including enzymes outside the current catalogue. Share the preparation, target reaction, assay and operating conditions so we can define an evaluation.
Which functional groups are available?
Our silica materials offer up to eight different functional groups. Contact us for the current surface-chemistry options and a project-specific recommendation.
Can you support novel use cases?
Yes. Bring us your immobilisation concept, including non-standard substrates, multi-step catalysis or other biomolecule-support applications. We can discuss feasibility, material requirements and a development programme.
How do we assess the commercial case?
Measure product output per catalyst campaign, replacement frequency, operating costs, downstream separation and the required equipment. Reuse alone is not a cost model; productive lifetime is what matters.
Can we start with an evaluation?
Yes. Discuss an initial support or biocatalyst evaluation with our technical team. We will agree the scope, preparation, quantity and supply terms before work starts.
BRING US YOUR NEXT PROCESS
Ambitious chemistry.
A practical next step.
Choose from our product range or ask us to develop an immobilisation solution for your process. Tell us which route you need and what you want to achieve.
sales@scientificandtechnical.com ↗Scientific and Technical Limited
John Eccles House · Oxford Science Park · UK
John Eccles House · Oxford Science Park · UK